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Scientific Papers

Scientific Papers

Humanization of N-glycosylation pathways in yeast
Nat Rev Microbiol  3 (2):119-28 2005 Feb
 
Advances in the production of human therapeutic proteins in yeast and filamentous fungi
Nature Biotechnology  22 (11): 1409-1414 2004 Nov 
Engineering of an artificial glycosylation pathway blocked in core oligosaccharide assembly in the yeast Pichia pastoris - production of complex humanized glycoproteins with terminal galactose
Glycobiology  14 (9): 757-766 2004 Jun
 
Functional analysis of the ALG3 gene encoding the Dol-P-Man: Man5GlcNAc2-PP-Dol mannosyltransferase enzyme of P. pastoris
Glycobiology  14 (5): 399-407 2003 Oct
 
Production of Complex Human Glycoproteins in Yeast
Science  301: 1244-1266 2003 Aug
 
Cloning and disruption of the PpURA5 gene and construction of a set of integration vectors for the stable genetic modification of Pichia pastoris
Yeast  20: 1279-1290 2003 Aug
 
Use of combinatorial genetic libraries to humanize N-linked glycosylation in the yeast Pichia pastoris
PNAS  100 (9): 5022-5027 2002 Dec

Glycosylation engineering in yeast: the advent of fully humanized yeast.
Curr Opin Biotechnol. 2007 Oct; 18 (5): 387-92. Epub 2007 Oct 24. Review.

Humanization of yeast to produce complex terminally sialylated glycoproteins.
Science. 2006 Sep 8; 313 (5792): 1441-3.

Optimization of humanized IgGs in glycoengineered Pichia pastoris.
Nat Biotechnol. 2006 Feb; 24 (2): 210-5. Epub 2006 Jan 22.

Cloning and disruption of the Pichia pastoris ARG1, ARG2, ARG3, HIS1, HIS2, HIS5, HIS6 genes and their use as auxotrophic markers.
Yeast. 2005 Mar; 22 (4): 295-304.


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